ZC3H12A

Across TCGA patient cohorts, ZC3H12A protein abundance is significantly associated with the RNA expression of many other genes, with 12,534 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZC3H12A-associated genes across cancer lineages are ZC3H12C, GKAP1, and PICK1. Each is linked with ZC3H12A in more than 4 cancer types. Because this analysis shows association rather than direction, both ZC3H12A-to-partner and partner-to-ZC3H12A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZC3H12A versus ZC3H12C in GBM, with a Pearson correlation of -0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC3H12A→partner) and Y-score (partner→ZC3H12A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ZC3H12C →	-0.944	-0.694	<.001	.001	3	5
GBM	GKAP1 →	-0.818	-0.548	<.001	<.001	3	5
HNSC	PICK1 →	-0.506	-0.272	.002	.001	3	4
LSCC	PCCB →	-0.769	-0.331	<.001	<.001	3	4
HNSC	IL1A →	+1.475	+0.277	<.001	.001	3	4
LSCC	EPHA7 →	-1.608	-0.358	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,534 associations by consensus.

ZC3H12A vs ZC3H12C — GBM

Explore this scatter interactively →