ZC3H12A

Across TCGA cell cohorts, ZC3H12A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,579 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZC3H12A-associated GO terms across cancer lineages are Cellular response to tumor necrosis factor, Response to tumor necrosis factor, and Regulation of response to cytokine stimulus. Each is linked with ZC3H12A in more than 19 cancer types. Because this analysis shows association rather than direction, both ZC3H12A-to-partner and partner-to-ZC3H12A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to tumor necrosis factor grouped by ZC3H12A-low versus ZC3H12A-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC3H12A→partner) and Y-score (partner→ZC3H12A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Cellular response to tumor necrosis factor →	+0.116	+1.985	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	Response to tumor necrosis factor →	+0.090	+2.304	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Regulation of response to cytokine stimulus →	+0.105	+2.101	<.001	<.001	3	16
PANCREAS	Regulation of protein deubiquitination →	+0.166	+1.869	<.001	<.001	3	16
PANCREAS	Cellular response to molecule of bacterial origin →	+0.091	+1.489	<.001	.004	3	16
LUNG_NSCLC_LUSC	Response to ionomycin →	+1.521	+1.921	.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,579 associations by consensus.

Cellular response to tumor necrosis factor by ZC3H12A expression — PANCREAS

Explore this box plot interactively →