ZBTB8A

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZBTB8A mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZBTB8A-associated genes across cancer lineages are TBC1D3. Each is linked with ZBTB8A in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB8A-to-partner and partner-to-ZBTB8A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBC1D3 grouped by ZBTB8A-low versus ZBTB8A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB8A→partner) and Y-score (partner→ZBTB8A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINETBC1D3 →+0.091+4.273<.001.00631
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

TBC1D3 by ZBTB8A expression — LARGE_INTESTINE

Box plot of TBC1D3 in ZBTB8A-low vs ZBTB8A-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration