ZBTB7A

Across TCGA patient cohorts, ZBTB7A protein abundance is significantly associated with the RNA expression of many other genes, with 10,830 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZBTB7A-associated genes across cancer lineages are ZC3H12A, WNK3, and DHRS12. Each is linked with ZBTB7A in more than 4 cancer types. Because this analysis shows association rather than direction, both ZBTB7A-to-partner and partner-to-ZBTB7A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZBTB7A versus ZC3H12A in HNSC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB7A→partner) and Y-score (partner→ZBTB7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZC3H12A →	+0.802	+0.240	<.001	<.001	3	5
UCEC	WNK3 →	-0.791	-0.192	.001	<.001	3	5
HNSC	DHRS12 →	-0.360	-0.132	.003	.004	3	4
LSCC	DNMT3A →	-0.609	-0.266	<.001	<.001	3	4
HNSC	KIAA1549 →	-1.039	-0.219	<.001	<.001	3	4
HNSC	TLCD5 →	-0.626	-0.198	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,830 associations by consensus.

ZBTB7A vs ZC3H12A — HNSC

Explore this scatter interactively →