ZBTB7A

Across TCGA cell cohorts, ZBTB7A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,896 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ZBTB7A-associated GO terms across cancer lineages are Positive regulation of anaphase-promoting complex-dependent catabolic process, Negative regulation of inflammasome-mediated signaling pathway, and Cilium movement involved in cell motility. Each is linked with ZBTB7A in more than 14 cancer types. Because this analysis shows association rather than direction, both ZBTB7A-to-partner and partner-to-ZBTB7A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of anaphase-promoting complex-dependent catabolic process grouped by ZBTB7A-low versus ZBTB7A-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB7A→partner) and Y-score (partner→ZBTB7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.122	+0.566	.006	.007	3	15
UPPER_AERODIGESTIVE_TRACT	Negative regulation of inflammasome-mediated signaling pathway →	+0.114	+0.827	<.001	.008	3	14
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.108	-0.955	<.001	<.001	3	14
STOMACH	Regulation of glycolytic process →	+0.072	+0.757	<.001	<.001	3	14
STOMACH	Regulation of nucleotide catabolic process →	+0.072	+0.757	<.001	<.001	3	14
STOMACH	Regulation of purine nucleotide catabolic process →	+0.072	+0.757	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,896 associations by consensus.

Positive regulation of anaphase-promoting complex-dependent catabolic process by ZBTB7A expression — LUNG_SCLC

Explore this box plot interactively →