ZBTB7A

Across TCGA cell cohorts, ZBTB7A mutation is significantly associated with the RNA expression of many other genes, with 293 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZBTB7A-associated genes across cancer lineages are BANF2, MROH2B, and OR10W1. Each is linked with ZBTB7A in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB7A-to-partner and partner-to-ZBTB7A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BANF2 grouped by ZBTB7A-low versus ZBTB7A-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB7A→partner) and Y-score (partner→ZBTB7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	BANF2 →	+0.035	+4.643	.003	.005	3	2
BLOOD_Lymphoma	MROH2B →	+0.087	+4.643	<.001	.005	3	2
BREAST	OR10W1 →	+0.013	+5.781	<.001	.001	3	2
BLOOD_Leukemia	ATF4 →	+0.453	+3.629	<.001	<.001	3	2
BLOOD_Leukemia	SESN2 →	+1.007	+2.837	.001	<.001	3	2
BLOOD_Leukemia	BBS7 →	+0.675	+3.290	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 293 associations by consensus.

BANF2 by ZBTB7A expression — BLOOD_Lymphoma

Explore this box plot interactively →