ZBTB44-DT

Across TCGA patient cohorts, ZBTB44-DT mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB44-DT-associated genes across cancer lineages are MIR7702, RNU6-1292P, and RNU6-1126P. Each is linked with ZBTB44-DT in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB44-DT-to-partner and partner-to-ZBTB44-DT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR7702 grouped by ZBTB44-DT-low versus ZBTB44-DT-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB44-DT→partner) and Y-score (partner→ZBTB44-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR7702 →	+0.757	+6.475	<.001	<.001	3	1
UCEC	RNU6-1292P →	+0.516	+4.868	<.001	.004	3	1
UCEC	RNU6-1126P →	+0.519	+4.750	<.001	.005	3	1
UCEC	IGHD3-16 →	+2.336	+4.095	<.001	.005	3	1
UCEC	RNU6-907P →	+0.555	+4.666	<.001	.001	3	1
UCEC	RNU6-192P →	+0.374	+4.267	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

MIR7702 by ZBTB44-DT expression — UCEC

Explore this box plot interactively →