Across TCGA cell cohorts, ZBTB3 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZBTB3-associated genes across cancer lineages are BHLHE23, NGF, and UGT2B4. Each is linked with ZBTB3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB3-to-partner and partner-to-ZBTB3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB3→partner) and Y-score (partner→ZBTB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	BHLHE23 →	+0.996	+3.691	.006	.005	3	1
BLOOD_Leukemia	NGF →	+0.240	+3.594	.004	.007	3	1
BLOOD_Leukemia	UGT2B4 →	+0.059	+4.177	<.001	.001	3	1
BLOOD_Leukemia	TGM6 →	+0.015	+4.569	<.001	.003	3	1
BLOOD_Leukemia	OR10K1 →	+0.340	+3.234	.006	.008	3	1
BLOOD_Leukemia	TBPL2 →	+0.114	+4.044	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

ZBTB3 survival (RNA) · tumor vs normal (RNA) · all ZBTB3 data types