Across TCGA cell cohorts, ZBTB14 mutation is significantly associated with the RNA expression of many other genes, with 35 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZBTB14-associated genes across cancer lineages are SSMEM1, S100G, and KCND3. Each is linked with ZBTB14 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB14-to-partner and partner-to-ZBTB14 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB14→partner) and Y-score (partner→ZBTB14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SSMEM1 →	+0.022	+3.029	.001	.003	3	1
LARGE_INTESTINE	S100G →	+1.023	+2.688	<.001	.008	3	1
LARGE_INTESTINE	KCND3 →	+0.343	+3.548	.001	.004	3	1
LARGE_INTESTINE	TFDP3 →	+0.019	+2.933	<.001	.003	3	1
LARGE_INTESTINE	SPANXN3 →	+0.137	+3.237	<.001	.001	3	1
LARGE_INTESTINE	TMEM233 →	+0.220	+2.933	.005	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

Exploration

ZBTB14 survival (RNA) · tumor vs normal (RNA) · all ZBTB14 data types