ZBTB11

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZBTB11 mutation is significantly associated with the RNA expression of many other genes, with 4,855 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB11-associated genes across cancer lineages are ELOCP5, DNM1P28, and DAOA. Each is linked with ZBTB11 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZBTB11-to-partner and partner-to-ZBTB11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ELOCP5 grouped by ZBTB11-low versus ZBTB11-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB11→partner) and Y-score (partner→ZBTB11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADELOCP5 →+0.069+4.506<.001.00433
SKCMDNM1P28 →+0.052+3.487<.001.00533
KIRPDAOA →+0.095+5.301<.001.00133
BRCARNU6-211P →+0.357+4.341<.001.00933
LUSCS100A7L2 →+0.152+4.606<.001.00633
CESCRNA5SP204 →+0.324+6.569<.001.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,855 associations by consensus.

ELOCP5 by ZBTB11 expression — STAD

Box plot of ELOCP5 in ZBTB11-low vs ZBTB11-high samples in STAD.

Explore this box plot interactively →

Exploration