Q-omics provides the consensus-scored DNM1P28 profile across patient tissues and cancer cell-line models. DNM1P28 expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, DNM1P28 is differentially expressed in 2, with the highest sampling consensus in BRCA. Additionally, DNM1P28 RNA expression shows 7,396 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight ACC, BRCA, and THYM as cancer lineages where DNM1P28 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for DNM1P28 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes DNM1P28 survival associations across molecular data types. DNM1P28 RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible DNM1P28 RNA expression–survival associations across cancer types. High DNM1P28 expression shows unfavorable associations in ACC, BRCA, KICH, OV, THCA and STAD. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .004). Together, the overview and detailed table identify ACC as the clearest survival context for DNM1P28 RNA expression.
This table summarizes DNM1P28 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in BRCA for RNA.
This table ranks reproducible tumor–normal expression differences for DNM1P28. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. DNM1P28 shows lower tumor expression in BRCA and LUSC. The BRCA box plot shows higher DNM1P28 RNA expression in normal versus tumor tissue (log2 FC = −0.015, t-test p = .007).
This table shows molecular features associated with DNM1P28 in patient tissues and cancer cell lines. In patient samples, DNM1P28 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
