ZAP70

Across TCGA patient cohorts, ZAP70 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,964 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZAP70-associated proteins across cancer lineages are WAS, WDFY4, and WIPF1. Each is linked with ZAP70 in more than 9 cancer types. Because this analysis shows association rather than direction, both ZAP70-to-partner and partner-to-ZAP70 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZAP70 versus WAS in GBM, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZAP70→partner) and Y-score (partner→ZAP70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	WAS →	+0.684	+0.777	<.001	<.001	3	10
LSCC	WDFY4 →	+0.585	+1.011	<.001	<.001	3	10
OV	WIPF1 →	+0.535	+0.903	<.001	<.001	3	10
GBM	PSMB10 →	+0.567	+0.634	<.001	<.001	3	10
OV	CD48 →	+1.133	+0.909	<.001	<.001	3	10
UCEC	CORO1A →	+0.727	+1.221	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,964 associations by consensus.

ZAP70 vs WAS — GBM

Explore this scatter interactively →