YY1

Across TCGA cell cohorts, YY1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,595 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible YY1-associated GO terms across cancer lineages are Monoubiquitinated protein deubiquitination, Protein localization to condensed chromosome, and Mitotic G2/M transition checkpoint. Each is linked with YY1 in more than 15 cancer types. Because this analysis shows association rather than direction, both YY1-to-partner and partner-to-YY1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Monoubiquitinated protein deubiquitination grouped by YY1-low versus YY1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (YY1→partner) and Y-score (partner→YY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Monoubiquitinated protein deubiquitination →	+0.159	+0.781	<.001	<.001	3	16
OESOPHAGUS	Protein localization to condensed chromosome →	+0.186	+0.722	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Mitotic G2/M transition checkpoint →	+0.090	+0.668	.004	.002	3	15
OESOPHAGUS	Negative regulation of transcription by RNA polymerase I →	+0.133	+0.798	<.001	<.001	3	15
BREAST	Immunoglobulin heavy chain V-D-J recombination →	+0.135	+0.538	.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of G2/M transition of mitotic cell cycle →	+0.085	+0.656	.003	.002	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,595 associations by consensus.

Monoubiquitinated protein deubiquitination by YY1 expression — STOMACH

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