YWHAQ

Across TCGA patient cohorts, YWHAQ RNA expression is significantly associated with the protein abundance of many other proteins, with 16,028 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible YWHAQ-associated proteins across cancer lineages are CLASP1, MCM7, and RRM2. Each is linked with YWHAQ in more than 6 cancer types. Because this analysis shows association rather than direction, both YWHAQ-to-partner and partner-to-YWHAQ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, YWHAQ versus CLASP1 in LSCC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (YWHAQ→partner) and Y-score (partner→YWHAQ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CLASP1 →	+0.335	+0.598	<.001	<.001	3	7
GBM	MCM7 →	+0.671	+0.441	<.001	<.001	3	7
BRCA	RRM2 →	+0.738	+0.564	<.001	<.001	3	6
GBM	SMC4 →	+0.633	+0.434	<.001	<.001	3	6
LSCC	MDM1_S601 →	-0.609	-0.741	<.001	<.001	3	6
PDAC	MECP2 →	-0.361	-0.274	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,028 associations by consensus.

YWHAQ vs CLASP1 — LSCC

Explore this scatter interactively →