YWHAQ

Across TCGA patient cohorts, YWHAQ mutation is significantly associated with the RNA expression of many other genes, with 401 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible YWHAQ-associated genes across cancer lineages are LINC01072, ELOCP18, and RN7SL169P. Each is linked with YWHAQ in more than 1 cancer types. Because this analysis shows association rather than direction, both YWHAQ-to-partner and partner-to-YWHAQ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01072 grouped by YWHAQ-low versus YWHAQ-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YWHAQ→partner) and Y-score (partner→YWHAQ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC01072 →	+0.143	+2.640	<.001	.003	3	2
SKCM	ELOCP18 →	+0.220	+4.076	<.001	.001	3	2
SKCM	RN7SL169P →	+0.063	+4.797	<.001	.003	3	2
LUAD	RNU6-391P →	+0.589	+7.930	<.001	.008	3	1
LUAD	WBP1LP5 →	+0.589	+7.930	<.001	.008	3	1
LUAD	MIR4432 →	+0.453	+7.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 401 associations by consensus.

LINC01072 by YWHAQ expression — UCEC

Explore this box plot interactively →