YWHAEP3

Across TCGA patient cohorts, YWHAEP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,928 significant associations in total. STAD shows the largest number of these associations.

The most reproducible YWHAEP3-associated GO terms across cancer lineages are Keratinocyte proliferation, Regulation of keratinocyte proliferation, and Endothelial cell morphogenesis. Each is linked with YWHAEP3 in more than 5 cancer types. Because this analysis shows association rather than direction, both YWHAEP3-to-partner and partner-to-YWHAEP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Keratinocyte proliferation grouped by YWHAEP3-low versus YWHAEP3-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (YWHAEP3→partner) and Y-score (partner→YWHAEP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Keratinocyte proliferation →	+0.070	+0.320	<.001	<.001	3	6
STAD	Regulation of keratinocyte proliferation →	+0.065	+0.199	<.001	<.001	3	5
STAD	Endothelial cell morphogenesis →	+0.070	+0.157	<.001	<.001	3	5
STAD	Regulation of defense response to fungus →	+0.040	+0.114	<.001	<.001	3	5
STAD	Cerebral cortex radially oriented cell migration →	+0.054	+0.112	<.001	<.001	3	5
CESC	Negative regulation of glucocorticoid metabolic process →	+0.066	+0.119	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,928 associations by consensus.

Keratinocyte proliferation by YWHAEP3 expression — ESCA

Explore this box plot interactively →