YWHAEP3

Across TCGA pan-cancer cohorts, YWHAEP3 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of YWHAEP3’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where YWHAEP3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types YWHAEP3 is over-expressed in tumor.

LUSC are the cancer types where YWHAEP3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in YWHAEP3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	All	+0.062	.041	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

YWHAEP3–LUSC

Open the LUSC breakdown →