YPEL5

Across TCGA patient cohorts, YPEL5 mutation is significantly associated with the RNA expression of many other genes, with 200 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible YPEL5-associated genes across cancer lineages are M6PRP1, MIR5700, and OR7E18P. Each is linked with YPEL5 in more than 2 cancer types. Because this analysis shows association rather than direction, both YPEL5-to-partner and partner-to-YPEL5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, M6PRP1 grouped by YPEL5-low versus YPEL5-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YPEL5→partner) and Y-score (partner→YPEL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	M6PRP1 →	+0.065	+5.337	<.001	.006	3	3
LUSC	MIR5700 →	+0.774	+4.984	<.001	.009	3	2
SKCM	OR7E18P →	+0.075	+5.513	<.001	.004	3	1
SKCM	SAGE2P →	+0.025	+6.624	.003	.001	3	1
SKCM	FAM90A24P →	+0.025	+5.362	<.001	.005	3	1
UCEC	CHODL →	-0.936	-3.459	.006	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 200 associations by consensus.

M6PRP1 by YPEL5 expression — LUSC

Explore this box plot interactively →