Across TCGA patient cohorts, XRCC6P5 mutation is significantly associated with the RNA expression of many other genes, with 2,953 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible XRCC6P5-associated genes across cancer lineages are TENT2, PPIHP1, and CDCA2. Each is linked with XRCC6P5 in more than 2 cancer types. Because this analysis shows association rather than direction, both XRCC6P5-to-partner and partner-to-XRCC6P5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (XRCC6P5→partner) and Y-score (partner→XRCC6P5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TENT2 →	+0.389	+2.354	.004	.003	3	3
LUAD	PPIHP1 →	+0.622	+2.185	<.001	.008	3	3
UCEC	CDCA2 →	+0.699	+2.600	<.001	<.001	3	3
UCEC	KIF9-AS1 →	+0.437	+1.789	<.001	.008	3	3
UCEC	UHRF1 →	+0.668	+1.818	.002	.002	3	2
UCEC	RNA5SP412 →	+0.518	+1.719	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,953 associations by consensus.

Exploration

XRCC6P5 survival (RNA) · tumor vs normal (RNA) · all XRCC6P5 data types