Across TCGA pan-cancer cohorts, XRCC6P5 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated XRCC6P5 data layer compared with 6 for mutation status.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher XRCC6P5 RNA is associated with better overall survival. In most high-consensus cancer types, elevated XRCC6P5 expression acts as an unfavorable survival marker, although some lineages such as LUSC and READ show a favorable association.
LUSC, BLCA, and UCS are the cancer types where XRCC6P5 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.