Across TCGA patient cohorts, XPOTP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,397 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible XPOTP1-associated proteins across cancer lineages are SHMT2, SSB, and MPHOSPH10. Each is linked with XPOTP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both XPOTP1-to-partner and partner-to-XPOTP1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (XPOTP1→partner) and Y-score (partner→XPOTP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SHMT2 →	+0.487	+0.342	<.001	.004	3	4
GBM	SSB →	+0.262	+0.191	.002	.001	3	4
LSCC	MPHOSPH10 →	+0.475	+0.184	<.001	<.001	3	4
LSCC	XPOT →	+0.581	+0.218	<.001	<.001	3	4
BRCA	WDR12 →	+0.459	+0.596	<.001	<.001	3	4
BRCA	RPL5 →	+0.265	+0.713	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,397 associations by consensus.

Exploration

XPOTP1 survival (RNA) · tumor vs normal (RNA) · all XPOTP1 data types