exportin for tRNA pseudogene 1Genealiases: XPO3P1 · dJ785G19.1
Q-omics provides the consensus-scored XPOTP1 profile across patient tissues and cancer cell-line models. XPOTP1 expression is associated with patient survival in 25 of 34 cancer types, with the highest sampling consensus in MESO. Among the 18 cancer types available for tumor–normal comparison, XPOTP1 is differentially expressed in 13, with the highest sampling consensus in COAD. Additionally, XPOTP1 RNA expression shows 17,902 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight MESO, COAD, and UVM as cancer lineages where XPOTP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for XPOTP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes XPOTP1 survival associations across molecular data types. XPOTP1 RNA expression shows survival associations in the most cancer types (25). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible XPOTP1 RNA expression–survival associations across cancer types. High XPOTP1 expression shows unfavorable associations in MESO, UVM, KICH, KIRP and LIHC, but favorable associations in KIRC. The MESO Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify MESO as the clearest survival context for XPOTP1 RNA expression.
This table summarizes XPOTP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 13. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for XPOTP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. XPOTP1 shows lower tumor expression in THCA and higher tumor expression in COAD, HNSC, LUAD, UCEC and LUSC. The COAD box plot shows higher XPOTP1 RNA expression in tumor versus normal tissue (log2 FC = +0.326, t-test p < 0.001).
This table shows molecular features associated with XPOTP1 in patient tissues and cancer cell lines. In patient samples, XPOTP1 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
