XKRY

Across TCGA patient cohorts, XKRY RNA expression is significantly associated with the go_rna of many other GO terms, with 68 significant associations in total. ESCA shows the largest number of these associations.

The most reproducible XKRY-associated GO terms across cancer lineages are Cerebellar Purkinje cell layer formation, Endothelial cell-matrix adhesion, and Response to gravity. Each is linked with XKRY in more than 1 cancer types. Because this analysis shows association rather than direction, both XKRY-to-partner and partner-to-XKRY results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cerebellar Purkinje cell layer formation grouped by XKRY-low versus XKRY-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (XKRY→partner) and Y-score (partner→XKRY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Cerebellar Purkinje cell layer formation →	-0.062	-0.004	<.001	.004	3	1
ESCA	Endothelial cell-matrix adhesion →	+0.100	+0.006	<.001	.005	3	1
ESCA	Response to gravity →	+0.130	+0.006	<.001	<.001	3	1
ESCA	Response to acidic pH →	+0.063	+0.005	.002	.001	3	1
ESCA	Glycolipid catabolic process →	+0.060	+0.005	.003	.001	3	1
STAD	Respiratory chain complex III assembly →	+0.063	+0.004	<.001	.003	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 68 associations by consensus.

Cerebellar Purkinje cell layer formation by XKRY expression — STAD

Explore this box plot interactively →