Q-omics provides the consensus-scored XKRY profile across patient tissues and cancer cell-line models. XKRY expression is associated with patient survival in 4 of 34 cancer types, with the highest sampling consensus in UCS. Additionally, XKRY RNA expression shows 1,196 significant gene co-expression associations, with the highest sampling consensus in ESCA. Together, these results highlight UCS, and ESCA as cancer lineages where XKRY shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes XKRY survival associations across molecular data types. XKRY RNA expression shows survival associations in the most cancer types (4). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

XKRY data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	4	UCS (108)	view →

This table ranks reproducible XKRY RNA expression–survival associations across cancer types. High XKRY expression shows unfavorable associations in UCS, OV, BLCA and ESCA. The UCS Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UCS as the clearest survival context for XKRY RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Tertile	All	0.102	0.688	<.001	108	view →
OV	OS	Tertile	II,III,IV	0.420	0.697	<.001	90	view →
BLCA	OS	Tertile	All	0.174	0.720	<.001	72	view →
ESCA	OS	Tertile	All	0.211	0.876	.028	18	view →

Pink = unfavorable, green = favorable. all 4 lineages →

XKRY-UCS (OS)

Kaplan–Meier survival curve for XKRY RNA expression in UCS: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with XKRY in patient tissues and cancer cell lines. In patient samples, XKRY shows the broadest associations at the RNA and protein expression levels, with ESCA recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	1,196	ESCA (710)	view →
Function (RNA)	68	ESCA (38)	view →