XKRY

Across TCGA pan-cancer cohorts, XKRY RNA is linked to patient survival in 4 of 34 cancer types, making it the most broadly survival-associated XKRY data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher XKRY RNA is associated with worse overall survival. In most high-consensus cancer types, elevated XKRY expression acts as an unfavorable survival marker.

UCS, OV, and BLCA are the cancer types where XKRY RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Tertile	All	0.102	0.688	<.001	108	view →
OV	OS	Tertile	II,III,IV	0.420	0.697	<.001	90	view →
BLCA	OS	Tertile	All	0.174	0.720	<.001	72	view →
ESCA	OS	Tertile	All	0.211	0.876	.028	18	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

XKRY–UCS (OS)

Open the UCS breakdown →