XIAPP3

Across TCGA patient cohorts, XIAPP3 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,693 significant associations in total. GBM shows the largest number of these associations.

The most reproducible XIAPP3-associated proteins across cancer lineages are RRM2, SMC2, and SPC24. Each is linked with XIAPP3 in more than 5 cancer types. Because this analysis shows association rather than direction, both XIAPP3-to-partner and partner-to-XIAPP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, XIAPP3 versus RRM2 in LUAD, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (XIAPP3→partner) and Y-score (partner→XIAPP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RRM2 →	+0.713	+0.472	<.001	.001	3	6
UCEC	SMC2 →	+0.649	+0.832	<.001	<.001	3	6
UCEC	SPC24 →	+0.628	+0.657	<.001	<.001	3	6
LSCC	MAD2L1 →	+0.427	+0.533	<.001	.002	3	6
LUAD	MKI67_S357 →	+1.266	+0.637	.001	.003	3	6
GBM	PRC1 →	+0.632	+0.635	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,693 associations by consensus.

XIAPP3 vs RRM2 — LUAD

Explore this scatter interactively →