XG

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, XG RNA expression is significantly associated with the protein abundance of many other proteins, with 10,809 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible XG-associated proteins across cancer lineages are P3H1, CD99, and CDH11. Each is linked with XG in more than 4 cancer types. Because this analysis shows association rather than direction, both XG-to-partner and partner-to-XG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, XG versus P3H1 in BRCA, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (XG→partner) and Y-score (partner→XG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAP3H1 →+0.541+0.935<.001<.00135
BRCACD99 →+0.629+1.212<.001<.00135
BRCACDH11 →+0.536+0.855<.001<.00135
COADCOL12A1 →+0.754+0.638<.001.00135
COADCOL1A2 →+0.696+0.609<.001.00135
COADCOL3A1 →+0.730+0.547<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,809 associations by consensus.

XG vs P3H1 — BRCA

Per-sample scatter of XG vs P3H1 in BRCA (Pearson r = 0.50).

Explore this scatter interactively →

Exploration