XG

Across TCGA cell cohorts, XG RNA expression is significantly associated with the go_rna of many other GO terms, with 2,400 significant associations in total. BONE shows the largest number of these associations.

The most reproducible XG-associated GO terms across cancer lineages are PML body organization, Response to triglyceride, and Regulation of phospholipid translocation. Each is linked with XG in more than 5 cancer types. Because this analysis shows association rather than direction, both XG-to-partner and partner-to-XG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PML body organization grouped by XG-low versus XG-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (XG→partner) and Y-score (partner→XG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	PML body organization →	-0.150	-3.087	<.001	<.001	3	6
BONE	Response to triglyceride →	-0.102	-2.934	<.001	<.001	3	5
BONE	Regulation of phospholipid translocation →	-0.163	-2.992	.002	.002	3	5
BONE	Positive regulation of phospholipid translocation →	-0.163	-2.992	.002	.002	3	5
BREAST	Viral process →	+0.055	+1.132	.006	.001	2	6
BREAST	Regulation of macroautophagy →	+0.045	+1.295	<.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,400 associations by consensus.

PML body organization by XG expression — BONE

Explore this box plot interactively →