WWTR1-IT1

Across TCGA patient cohorts, WWTR1-IT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,375 significant associations in total. GBM shows the largest number of these associations.

The most reproducible WWTR1-IT1-associated proteins across cancer lineages are WWTR1, FSCN1_S39, and ARHGEF26_S222. Each is linked with WWTR1-IT1 in more than 5 cancer types. Because this analysis shows association rather than direction, both WWTR1-IT1-to-partner and partner-to-WWTR1-IT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WWTR1-IT1 versus WWTR1 in GBM, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WWTR1-IT1→partner) and Y-score (partner→WWTR1-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	WWTR1 →	+0.446	+0.827	<.001	<.001	3	6
CCRCC	FSCN1_S39 →	+0.519	+0.559	.001	.001	3	4
HNSC	ARHGEF26_S222 →	+0.751	+0.781	.001	<.001	3	4
GBM	S100A10 →	+0.464	+0.697	<.001	<.001	3	4
UCEC	LMNA_S22 →	+0.700	+0.947	.002	.001	3	4
LSCC	UBXN7 →	+0.590	+0.844	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,375 associations by consensus.

WWTR1-IT1 vs WWTR1 — GBM

Explore this scatter interactively →