WWTR1-AS1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, WWTR1-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,503 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WWTR1-AS1-associated proteins across cancer lineages are TP53BP1_S398, MLF1_S34, and MELTF. Each is linked with WWTR1-AS1 in more than 3 cancer types. Because this analysis shows association rather than direction, both WWTR1-AS1-to-partner and partner-to-WWTR1-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WWTR1-AS1 versus TP53BP1_S398 in LSCC, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WWTR1-AS1→partner) and Y-score (partner→WWTR1-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCTP53BP1_S398 →+0.550+0.342<.001<.00134
LUADMLF1_S34 →+0.868+0.303<.001.00634
HNSCMELTF →+0.749+0.381<.001<.00134
LSCCFXR1 →+0.453+0.481<.001<.00134
LUADSFXN3 →-0.306-0.199.005.00334
LSCCDBR1 →+0.314+0.356<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,503 associations by consensus.

WWTR1-AS1 vs TP53BP1_S398 — LSCC

Per-sample scatter of WWTR1-AS1 vs TP53BP1_S398 in LSCC (Pearson r = 0.48).

Explore this scatter interactively →

Exploration