WWTR1-AS1

Across TCGA pan-cancer cohorts, WWTR1-AS1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated WWTR1-AS1 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher WWTR1-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated WWTR1-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and KIRP show a favorable association.

UCS, KIRP, and UCEC are the cancer types where WWTR1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Median	II,III,IV	0.550	0.136	<.001	104	view →
KIRP	OS	Tertile	All	0.970	0.842	<.001	94	view →
UCEC	DFS	Quartile	All	0.518	0.802	<.001	90	view →
LGG	OS	Median	All	0.342	0.520	<.001	46	view →
LIHC	OS	Quartile	II,III,IV	0.298	0.699	<.001	30	view →
COAD	DFS	Tertile	All	0.609	0.752	.005	29	view →
LUAD	DFS	Median	All	0.601	0.724	<.001	25	view →
LUSC	OS	Median	All	0.809	0.714	.019	15	view →
KIRC	OS	Quartile	II,III,IV	0.724	0.446	.015	10	view →
TGCT	DFS	Quartile	All	0.744	0.923	.043	10	view →
ACC	DFS	Quartile	All	0.149	0.631	.013	7	view →
SKCM	OS	Tertile	All	0.739	0.822	.010	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

WWTR1-AS1–UCS (DFS)

Open the UCS breakdown →