WSPAR

Across TCGA patient cohorts, WSPAR RNA expression is significantly associated with the go_rna of many other GO terms, with 6,489 significant associations in total. STAD shows the largest number of these associations.

The most reproducible WSPAR-associated GO terms across cancer lineages are Positive regulation of DNA metabolic process, Positive regulation of double-strand break repair, and Translational initiation. Each is linked with WSPAR in more than 13 cancer types. Because this analysis shows association rather than direction, both WSPAR-to-partner and partner-to-WSPAR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA metabolic process grouped by WSPAR-low versus WSPAR-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WSPAR→partner) and Y-score (partner→WSPAR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of DNA metabolic process →	+0.082	+0.099	<.001	<.001	3	13
STAD	Positive regulation of double-strand break repair →	+0.075	+0.085	<.001	<.001	3	13
STAD	Translational initiation →	+0.088	+0.082	<.001	<.001	3	12
STAD	Mitochondrial membrane organization →	+0.086	+0.084	<.001	<.001	3	12
COAD	Protein stabilization →	+0.083	+0.082	<.001	.004	1	14
STAD	Macromolecule methylation →	+0.080	+0.094	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,489 associations by consensus.

Positive regulation of DNA metabolic process by WSPAR expression — STAD

Explore this box plot interactively →