WSB2

Across TCGA patient cohorts, WSB2 mutation is significantly associated with the RNA expression of many other genes, with 473 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WSB2-associated genes across cancer lineages are RN7SL237P, LINC00904, and LINC02647. Each is linked with WSB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both WSB2-to-partner and partner-to-WSB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL237P grouped by WSB2-low versus WSB2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WSB2→partner) and Y-score (partner→WSB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL237P →	+0.146	+5.418	<.001	.005	3	2
UCEC	LINC00904 →	+0.147	+2.370	.001	.008	3	2
UCEC	LINC02647 →	+0.097	+3.598	<.001	.002	3	2
UCEC	ZNF722P →	+0.191	+2.608	<.001	.004	3	2
UCEC	BNIP3P6 →	+0.044	+5.019	<.001	.001	3	2
UCEC	LINC02305 →	+0.118	+2.957	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 473 associations by consensus.

RN7SL237P by WSB2 expression — CESC

Explore this box plot interactively →