Across TCGA patient cohorts, WNT7B mutation is significantly associated with the RNA expression of many other genes, with 1,986 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WNT7B-associated genes across cancer lineages are RNU6-1205P, GHITM, and MTND4P8. Each is linked with WNT7B in more than 2 cancer types. Because this analysis shows association rather than direction, both WNT7B-to-partner and partner-to-WNT7B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT7B→partner) and Y-score (partner→WNT7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-1205P →	+0.442	+2.861	<.001	.009	3	3
UCEC	GHITM →	+0.596	+2.906	.004	.002	3	3
CESC	MTND4P8 →	+0.018	+5.584	<.001	.001	3	2
CESC	OR4A14P →	+0.023	+4.342	<.001	.007	3	2
ESCA	LINC00328-2P →	+0.383	+4.392	<.001	.006	3	2
UCEC	SENP3-EIF4A1 →	+0.137	+2.267	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,986 associations by consensus.

Exploration

WNT7B survival (RNA) · tumor vs normal (RNA) · all WNT7B data types