WNT7A

Across TCGA patient cohorts, WNT7A mutation is significantly associated with the RNA expression of many other genes, with 741 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WNT7A-associated genes across cancer lineages are FAM242A, RNU6-1318P, and TEX28. Each is linked with WNT7A in more than 2 cancer types. Because this analysis shows association rather than direction, both WNT7A-to-partner and partner-to-WNT7A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM242A grouped by WNT7A-low versus WNT7A-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT7A→partner) and Y-score (partner→WNT7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FAM242A →	+0.248	+3.251	.002	.002	3	3
SKCM	RNU6-1318P →	+0.129	+2.366	<.001	.003	3	3
BRCA	TEX28 →	+0.014	+4.757	<.001	.003	3	2
BLCA	MRGPRX9P →	+0.090	+5.289	<.001	.003	3	2
LGG	RNU6-332P →	+0.308	+7.977	<.001	.007	3	2
SKCM	GTF2F2P2 →	+0.014	+2.648	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 741 associations by consensus.

FAM242A by WNT7A expression — LUAD

Explore this box plot interactively →