Q-omics provides the consensus-scored TEX28 profile across patient tissues and cancer cell-line models. TEX28 expression is associated with patient survival in 5 of 34 cancer types, with the highest sampling consensus in CESC. Among the 18 cancer types available for tumor–normal comparison, TEX28 is differentially expressed in 1, with the highest sampling consensus in UCEC. Additionally, TEX28 RNA expression shows 6,019 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight CESC, UCEC, and STAD as cancer lineages where TEX28 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for TEX28 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes TEX28 survival associations across molecular data types. TEX28 RNA expression shows survival associations in the most cancer types (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible TEX28 RNA expression–survival associations across cancer types. High TEX28 expression shows unfavorable associations in CESC, LAML, GBM, STAD and BLCA. The CESC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .003). Together, the overview and detailed table identify CESC as the clearest survival context for TEX28 RNA expression.
This table summarizes TEX28 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in UCEC for RNA.
This table ranks reproducible tumor–normal expression differences for TEX28. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. TEX28 shows higher tumor expression in UCEC. The UCEC box plot shows higher TEX28 RNA expression in tumor versus normal tissue (log2 FC = +0.017, t-test p = .022).
This table shows molecular features associated with TEX28 in patient tissues and cancer cell lines. In patient samples, TEX28 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set. In cancer cell lines, TEX28 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in URINARY_TRACT, while CRISPR and shRNA rows add functional-dependency signals in PANCREAS and LUNG_NSCLC_LUAD.
