Across TCGA pan-cancer cohorts, TEX28 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of TEX28’s most consistent transcriptional readouts.
The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where TEX28 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TEX28 is over-expressed in tumor.
UCEC are the cancer types where TEX28 tumor–normal differential expression is most reproducible.