WNT5B

Across TCGA patient cohorts, WNT5B protein abundance is significantly associated with the RNA expression of many other genes, with 14,566 significant associations in total. GBM shows the largest number of these associations.

The most reproducible WNT5B-associated genes across cancer lineages are MIR8082, CGB3, and FOXB1. Each is linked with WNT5B in more than 1 cancer types. Because this analysis shows association rather than direction, both WNT5B-to-partner and partner-to-WNT5B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WNT5B versus MIR8082 in LSCC, with a Pearson correlation of -0.81.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT5B→partner) and Y-score (partner→WNT5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MIR8082 →	-1.307	-1.065	<.001	<.001	3	2
BRCA	CGB3 →	+0.250	+0.987	.003	.006	3	1
BRCA	FOXB1 →	+0.066	+0.987	.005	.006	3	1
BRCA	ULK4P3 →	+0.150	+1.302	.003	.002	3	1
BRCA	SNORD93 →	+2.496	+0.987	<.001	.006	3	1
BRCA	RN7SL806P →	+0.660	+0.987	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,566 associations by consensus.

WNT5B vs MIR8082 — LSCC

Explore this scatter interactively →