WNT5B

Across TCGA cell cohorts, WNT5B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,499 significant associations in total. BONE shows the largest number of these associations.

The most reproducible WNT5B-associated GO terms across cancer lineages are Positive regulation of cytoskeleton organization, Lactate metabolic process, and Regulation of heart rate by chemical signal. Each is linked with WNT5B in more than 10 cancer types. Because this analysis shows association rather than direction, both WNT5B-to-partner and partner-to-WNT5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cytoskeleton organization grouped by WNT5B-low versus WNT5B-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT5B→partner) and Y-score (partner→WNT5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of cytoskeleton organization →	+0.084	+3.298	<.001	<.001	3	11
BREAST	Lactate metabolic process →	+0.197	+2.718	<.001	<.001	3	11
BONE	Regulation of heart rate by chemical signal →	+0.541	+3.392	<.001	<.001	3	11
BONE	Positive regulation of natural killer cell activation →	+0.323	+3.629	<.001	<.001	3	10
BONE	Chondroblast differentiation →	+1.187	+2.472	<.001	<.001	3	10
BONE	Positive regulation of cell-substrate adhesion →	+0.153	+2.954	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,499 associations by consensus.

Positive regulation of cytoskeleton organization by WNT5B expression — BONE

Explore this box plot interactively →