WNT4

Across TCGA cell cohorts, WNT4 RNA expression is significantly associated with the RNA expression of many other genes, with 5,548 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible WNT4-associated genes across cancer lineages are JAG2, TRIM29, and NECTIN4. Each is linked with WNT4 in more than 5 cancer types. Because this analysis shows association rather than direction, both WNT4-to-partner and partner-to-WNT4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WNT4 versus JAG2 in URINARY_TRACT, with a Pearson correlation of 0.59.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT4→partner) and Y-score (partner→WNT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	JAG2 →	+2.554	+1.459	<.001	<.001	3	6
URINARY_TRACT	TRIM29 →	+5.943	+1.461	<.001	<.001	3	6
URINARY_TRACT	NECTIN4 →	+3.215	+1.199	<.001	<.001	3	6
URINARY_TRACT	ITPKC →	+1.447	+1.558	<.001	<.001	3	6
LUNG_NSCLC_LUAD	ZNF641 →	+1.258	+0.966	<.001	<.001	3	5
LUNG_SCLC	FOXO6 →	+1.810	+1.509	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,548 associations by consensus.

WNT4 vs JAG2 — URINARY_TRACT

Explore this scatter interactively →