WNT2

Across TCGA cell cohorts, WNT2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,623 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WNT2-associated genes across cancer lineages are MAP7, BCAS1, and DBN1. Each is linked with WNT2 in more than 8 cancer types. Because this analysis shows association rather than direction, both WNT2-to-partner and partner-to-WNT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WNT2 versus MAP7 in BREAST, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT2→partner) and Y-score (partner→WNT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	MAP7 →	+2.297	+1.861	<.001	<.001	3	9
BREAST	BCAS1 →	+4.033	+1.644	<.001	<.001	3	7
URINARY_TRACT	DBN1 →	-2.397	-1.487	<.001	.008	3	6
BREAST	IYD →	+1.295	+1.096	<.001	<.001	3	6
OESOPHAGUS	GMDS →	+1.502	+1.334	<.001	.002	3	5
OESOPHAGUS	GAREM1 →	+0.728	+0.736	.003	.008	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,623 associations by consensus.

WNT2 vs MAP7 — BREAST

Explore this scatter interactively →