WNT10B

Across TCGA patient cohorts, WNT10B RNA expression is significantly associated with the protein abundance of many other proteins, with 14,468 significant associations in total. GBM shows the largest number of these associations.

The most reproducible WNT10B-associated proteins across cancer lineages are PRKCB, CARMIL2_S1381, and RTN1. Each is linked with WNT10B in more than 5 cancer types. Because this analysis shows association rather than direction, both WNT10B-to-partner and partner-to-WNT10B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WNT10B versus PRKCB in GBM, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WNT10B→partner) and Y-score (partner→WNT10B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRKCB →	+0.546	+0.938	<.001	<.001	3	6
PDAC	CARMIL2_S1381 →	+0.962	+0.340	<.001	<.001	3	6
CCRCC	RTN1 →	+0.610	+0.412	<.001	<.001	3	5
CCRCC	SYK →	+0.418	+0.374	<.001	<.001	3	5
BRCA	RASAL3 →	+0.408	+0.613	<.001	<.001	3	5
GBM	SEPTIN6 →	+0.341	+0.646	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,468 associations by consensus.

WNT10B vs PRKCB — GBM

Explore this scatter interactively →