WIPI1

Across TCGA cell cohorts, WIPI1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,819 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible WIPI1-associated genes across cancer lineages are MTO1, CDK6, and DNMT3A. Each is linked with WIPI1 in more than 4 cancer types. Because this analysis shows association rather than direction, both WIPI1-to-partner and partner-to-WIPI1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WIPI1 versus MTO1 in LUNG_SCLC, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WIPI1→partner) and Y-score (partner→WIPI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	MTO1 →	+0.793	+0.817	<.001	<.001	3	5
BLOOD_Leukemia	CDK6 →	-1.841	-0.892	<.001	.002	3	4
BLOOD_Leukemia	DNMT3A →	-1.659	-1.270	<.001	<.001	3	4
BLOOD_Myeloma	FBRS →	-1.020	-1.002	<.001	.003	3	4
BLOOD_Myeloma	NABP1 →	-1.223	-0.901	.005	.001	3	4
BLOOD_Leukemia	C6orf201 →	-0.295	-0.875	.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,819 associations by consensus.

WIPI1 vs MTO1 — LUNG_SCLC

Explore this scatter interactively →