WHAMMP2

Across TCGA patient cohorts, WHAMMP2 mutation is significantly associated with the RNA expression of many other genes, with 63 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WHAMMP2-associated genes across cancer lineages are OR4K1, SAA3P, and RPL7L1P11. Each is linked with WHAMMP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both WHAMMP2-to-partner and partner-to-WHAMMP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4K1 grouped by WHAMMP2-low versus WHAMMP2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WHAMMP2→partner) and Y-score (partner→WHAMMP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	OR4K1 →	+0.048	+5.136	.008	.002	3	1
COAD	SAA3P →	+0.117	+4.730	<.001	.001	3	1
UCEC	RPL7L1P11 →	+0.147	+3.769	.001	<.001	3	1
UCEC	CACNG5 →	+1.073	+3.757	<.001	.004	3	1
UCEC	MIRLET7A1 →	+0.577	+2.867	.004	.007	3	1
UCEC	RNU6-1082P →	+0.363	+3.814	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 63 associations by consensus.

OR4K1 by WHAMMP2 expression — COAD

Explore this box plot interactively →