WFDC5

Across TCGA patient cohorts, WFDC5 protein abundance is significantly associated with the RNA expression of many other genes, with 600 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible WFDC5-associated genes across cancer lineages are RNU6-731P, APOBEC3H, and NOMO3. Each is linked with WFDC5 in more than 1 cancer types. Because this analysis shows association rather than direction, both WFDC5-to-partner and partner-to-WFDC5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WFDC5 versus RNU6-731P in HNSC, with a Pearson correlation of -0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WFDC5→partner) and Y-score (partner→WFDC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU6-731P →	-2.090	-1.663	.001	.005	3	2
HNSC	APOBEC3H →	-1.274	-1.673	<.001	.001	3	1
HNSC	NOMO3 →	-1.041	-1.920	<.001	<.001	3	1
HNSC	PRKAG2 →	-0.990	-1.469	<.001	<.001	3	1
HNSC	RIC1 →	-0.671	-1.714	<.001	.001	3	1
HNSC	TRDMT1 →	-1.010	-1.628	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 600 associations by consensus.

WFDC5 vs RNU6-731P — HNSC

Explore this scatter interactively →