WFDC5

Across TCGA cell cohorts, WFDC5 RNA expression is significantly associated with the go_rna of many other GO terms, with 466 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible WFDC5-associated GO terms across cancer lineages are Transepithelial water transport, Cellular response to glucocorticoid stimulus, and Regulation of p38MAPK cascade. Each is linked with WFDC5 in more than 5 cancer types. Because this analysis shows association rather than direction, both WFDC5-to-partner and partner-to-WFDC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transepithelial water transport grouped by WFDC5-low versus WFDC5-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WFDC5→partner) and Y-score (partner→WFDC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Transepithelial water transport →	+1.281	+1.046	.006	.008	2	6
UPPER_AERODIGESTIVE_TRACT	Cellular response to glucocorticoid stimulus →	+0.070	+1.005	.002	.009	3	4
UPPER_AERODIGESTIVE_TRACT	Regulation of p38MAPK cascade →	+0.170	+1.865	<.001	.001	3	3
UPPER_AERODIGESTIVE_TRACT	Regulation of autophagy of mitochondrion →	+0.085	+1.649	<.001	.001	3	3
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular mRNA localization →	+0.150	+1.199	<.001	.001	3	3
UPPER_AERODIGESTIVE_TRACT	Gap junction-mediated intercellular transport →	+1.305	+1.640	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 466 associations by consensus.

Transepithelial water transport by WFDC5 expression — OESOPHAGUS

Explore this box plot interactively →