WFDC11

RNA expression — cross-omics
Cross-omicsRNA → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, WFDC11 RNA expression is significantly associated with the mutation status of many other genes, with 116 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible WFDC11-associated genes across cancer lineages are SP100, ZNF813, and ZNF254. Each is linked with WFDC11 in more than 1 cancer types. Because this analysis shows association rather than direction, both WFDC11-to-partner and partner-to-WFDC11 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WFDC11→partner) and Y-score (partner→WFDC11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUSCSP100 →+4.643+0.053.008<.00132
OESOPHAGUSZNF813 →+4.906+0.046.006<.00132
OESOPHAGUSZNF254 →+4.906+0.046.006<.00132
BREASTKIF21A →+4.196+0.033.006<.00132
BREASTSETBP1 →+4.196+0.033.006<.00132
BLOOD_MyelomaPHYKPL →+4.754+0.112<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 116 associations by consensus.

Exploration