Across TCGA patient cohorts, WFDC10B mutation is significantly associated with the RNA expression of many other genes, with 215 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WFDC10B-associated genes across cancer lineages are LINC00634, RN7SL711P, and NCLP2. Each is linked with WFDC10B in more than 1 cancer types. Because this analysis shows association rather than direction, both WFDC10B-to-partner and partner-to-WFDC10B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WFDC10B→partner) and Y-score (partner→WFDC10B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC00634 →	+0.579	+3.542	.003	.002	3	2
SKCM	RN7SL711P →	+0.098	+2.430	<.001	.007	3	1
SKCM	NCLP2 →	+0.015	+2.669	.001	.007	3	1
SKCM	CTDSPL2P1 →	+0.009	+3.095	.007	.007	3	1
SKCM	FOXD2-AS1 →	+0.931	+3.198	.002	.009	3	1
SKCM	RN7SL552P →	+0.122	+2.361	.005	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 215 associations by consensus.

Exploration

WFDC10B survival (RNA) · tumor vs normal (RNA) · all WFDC10B data types