Across TCGA patient cohorts, WFDC10B mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WFDC10B-associated genes across cancer lineages are aDC, Endothelial cells, and Epithelial cells. Each is linked with WFDC10B in more than 1 cancer types. Because this analysis shows association rather than direction, both WFDC10B-to-partner and partner-to-WFDC10B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WFDC10B→partner) and Y-score (partner→WFDC10B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	aDC →	-0.101	-2.990	.037	.036	3	1
UCEC	Endothelial cells →	-0.042	-3.127	.046	.020	3	1
UCEC	Epithelial cells →	-0.112	-3.161	.004	.019	3	1
UCEC	Keratinocytes →	-0.016	-3.041	.033	.021	3	1
UCEC	Sebocytes →	-0.037	-3.148	.006	.020	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

WFDC10B survival (RNA) · tumor vs normal (RNA) · all WFDC10B data types