Across TCGA cell cohorts, WFDC10B RNA expression is significantly associated with the go_rna of many other GO terms, with 1,613 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible WFDC10B-associated GO terms across cancer lineages are Regulation of proteolysis, Positive regulation of proteolysis, and Negative regulation of immune response. Each is linked with WFDC10B in more than 8 cancer types. Because this analysis shows association rather than direction, both WFDC10B-to-partner and partner-to-WFDC10B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WFDC10B→partner) and Y-score (partner→WFDC10B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of proteolysis →	+0.089	+0.179	<.001	.006	2	9
PANCREAS	Positive regulation of proteolysis →	+0.079	+0.422	.002	.006	3	7
LUNG_NSCLC_LUAD	Negative regulation of immune response →	+0.063	+0.481	<.001	.007	2	8
LARGE_INTESTINE	Negative regulation of leukocyte cell-cell adhesion →	+0.069	+0.431	<.001	<.001	3	6
PANCREAS	Negative regulation of cell-cell adhesion →	+0.082	+0.486	<.001	.007	3	6
PANCREAS	Negative regulation of proteolysis →	+0.106	+0.603	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,613 associations by consensus.

Exploration

WFDC10B survival (RNA) · tumor vs normal (RNA) · all WFDC10B data types